Hyperglycemia and the Fate of Apparent Diffusion Coefficient–Defined Ischemic Penumbra
نویسندگان
چکیده
منابع مشابه
Hyperglycemia and the fate of apparent diffusion coefficient-defined ischemic penumbra.
BACKGROUND AND PURPOSE Previous data have shown the feasibility of identifying ischemic penumbra in patients with acute stroke by using a semiautomated analysis of ADC maps. Here, we investigated whether the fate of ADC-defined penumbra was altered by HG. We also examined the interaction between HG and arterial recanalization on infarct growth. MATERIALS AND METHODS We examined 94 patients by...
متن کاملViability thresholds of ischemic penumbra of hyperacute stroke defined by perfusion-weighted MRI and apparent diffusion coefficient.
BACKGROUND AND PURPOSE The penumbra of ischemic stroke consists of hypoperfused, but not irreversibly damaged, tissue surrounding the ischemic core. The purpose of this study was to determine viability thresholds in the ischemic penumbra, defined as the perfusion/diffusion mismatch in hyperacute stroke, by the use of diffusion- and perfusion-weighted MRI (DWI and PWI, respectively). METHODS D...
متن کاملThe cerebral ischemic penumbra.
When neuronal activity is suppressed by ischemia of sufficient severity, maintained for a long enough period of time, permanent clinical deficit can be accompanied by radiographic signs of cerebral infarction and histological evidence of ischemic damage. Recent work suggests that this is not an all-ornone event. Between the most densely ischemic region and the more normally perfused brain, an i...
متن کاملTargeting the ischemic penumbra.
BACKGROUND In the last 3 decades, and from a therapeutic point of view, the classical concept of ischemic penumbra based on hemodynamic and electrophysiological parameters has loosened up the rigidity of therapeutic windows in acute stroke management. Thirty years later, the ischemic penumbra is an evolved concept that presents more applications. Thus, the ischemic penumbra is a diagnostic targ...
متن کاملFate of the penumbra after mechanical thrombectomy.
BACKGROUND AND PURPOSE In acute stroke, CTP is often used to visualize the endangered brain areas, including the ischemic core and the penumbra. Our goal was to assess the evolution of the infarct after mechanical thrombectomy and to analyze the interventional factors determining the fate of the penumbra. MATERIALS AND METHODS All patients receiving mechanical thrombectomy in the anterior cir...
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ژورنال
عنوان ژورنال: American Journal of Neuroradiology
سال: 2011
ISSN: 0195-6108,1936-959X
DOI: 10.3174/ajnr.a2407